massivan
2022-12-20 00:42:43 UTC
https://www.cdc.gov/media/transcripts/t030315.htm
CDC Telebriefing Transcript
CDC's Response to Atypical Pneumonia in
Southeast Asia and Canada
March 15, 2003
MR. SKINNER: Thank you, Gwen, and thank you all for joining us. We're
going to get right to it, and with us on the call is the Secretary of
the Department of Health and Human Services, Mr. Tommy Thompson, who's
going to deliver some brief remarks, and then he has to run. We'll then
turn the call over to Dr. Julie Gerberding, and then we'll take your Q's
and A's.
So Secretary Thompson, please go, please.
SECRETARY THOMPSON: Thank you very much Tom, and Gwen, and Julie, and
Jerry. Thank you very much for allowing me to come on this
teleconference. I'm at O'Hare Airfield, and I'm going to be on a plane
in six minutes to go back to Washington, D.C. But I want to thank all of
you today for taking time today to join us for this telebriefing for an
update on the outbreak of what we consider a very severe acute
respiratory syndrome in Asia. We decided to have this telebriefing on
Saturday because this is a situation that we wanted to involve you in
very quickly, and we want you to have the most updated information.
Health officials around the world are taking this situation very
seriously. In fact, I had a teleconference with the World Health
Organization on Thursday at early morning, and I'm going to have another
one either tomorrow afternoon or Monday morning with the people at World
Health Organization. But under the great leadership of Dr. Julie
Gerberding at the CDC. the Department of Health and Human Services is
applying a full court press to learn more about this outbreak and how it
might impact on the United States.
Staff in the HHS Department and CDC Emergency Operations Center are
already working around the clock to assist officials from the World
Health Organization, as I mentioned, as they respond to this outbreak.
We've also contacted the Ministry of Health, my counterpart in China,
and I had a face-to-face meeting with the Deputy Minister of Health
about a week ago, a week to 10 days ago, asking them to make sure that
they would cooperate with us because we have to have their willingness
and their access into China to make sure that we can get to the root
causes of this particular disease.
We are doing everything humanly possible to learn what is causing this
outbreak, how to treat patients and how to prevent the spread to others.
I hope we're able to get to the bottom of this as soon as possible, as I
know all of you are and, certainly, the people and the wonderful efforts
at CDC.
Now, I'd like to turn this to Dr. Gerberding to provide you more
specifics on how the department is going to respond to this outbreak and
be able to give you updated information. Thank you very much, Julie, for
giving me this opportunity to address this group, and I wish you luck,
and I'll be talking to you as soon as I land in Washington, D.C.
ANNOUNCER: Thanks, sir. We really appreciate you joining in. Have a safe
journey home.
MR. SKINNER: Now I'd like to turn it over to Dr. Julie Gerberding,
Director of CDC. The name is spelled G-E-R-B-E-R-D-I-N-G. And she's
going to take just a few moments to talk a little bit about what we are
doing to organize our response to this outbreak.
DR. GERBERDING: Thank you. I wanted to start by explaining why we are
doing this on a Saturday. I'm fully aware this is not the optimal time
to do a media briefing, but as the Secretary said, the situation is
evolving very quickly, and we really do need to get the information out.
And, hopefully, you will appreciate that getting information out any
time is better than no information.
So we're going to tell you what we know today and recognize that this is
ongoing, and we'll be updating you as regularly as we have new
information. You will also be able to find information on the WHO
website, which is their main mechanism for providing international
summaries of these health data. And we will have links and so forth on
our website as we go forward.
The situation today is that WHO has received reports of more than 150
new or suspected cases of a syndrome called Severe Acute Respiratory
Syndrome, which is basically a very severe pneumonia-like illness that
is being reported from a growing list of countries, including China,
Hong Kong, Indonesia, Philippines, Singapore, Thailand and Vietnam. In
addition, the case reports from Canada. No cases have been identified in
the United States, but travelers through the United States who have been
in contact or have traveled to the affected areas are under
investigation to be sure that their time here did not result in exposure
and an opportunity for persons to acquire the illness in this country.
Obviously, this is a very early stage of the investigation, and given
the high prevalence of travel through Southeast Asia, we are alerting
our public health communities and our clinicians to be on the lookout
for cases, and I'll say in a couple of minutes what some of the other
steps that we are taking are at this point in time.
We have activated CDC's Emergency Operation Center to manage this
complex international multijurisdictional outbreak. Our role is to
assist WHO and health officials in the affected countries, in particular
in the area of epidemiologic investigation, laboratory diagnosis, and
assessment of prevention intervention. We have as our current priority
the detection of new cases using WHO case definition which I'll just
briefly review for you.
WHO is defining a case as someone with a fever greater than 38 degrees
Celsius (Editor's Note: 100.4 degrees Fahrenheit), respiratory symptoms
which could be cough, shortness of breath or difficulty breathing, and
either close contact with someone who's already been diagnosed with this
syndrome or recent travel to areas reporting cases of the syndrome.
We recognize, because we do not have an etiologic diagnosis or a
laboratory test for this illness right now, that this is a nonspecific
case definition and may include people who really don't have the
syndrome at all, may have some other more common respiratory illnesses,
but it is a starting point for investigation. And as we either rule in
or rule out cases as we go forward, the number of cases meeting the
syndrome is expected to change.
Our priority also is on communication. And you can expect us to be
providing you with regular updates as we go forward. As I mentioned, the
Web sites will be good resources, but we are also taking a number of
steps to put information out to a variety of collaborating partners.
These steps include sending health alerts to the public health and the
medical community. Later today we will be issuing guidance to clinicians
about the case definition, the isolation recommendation, and what we can
say about treatment and prophylaxis at this point in time.
We assume that this is spread person to person because we're seeing a
large proportion of the cases in Asia among health care workers who were
caring for the ill patients or household contacts of ill patients. We
are recommending precautions to prevent airborne spreads, droplet spread
and direct contact spread until we have further information. And so that
means we're erring on the side of caution until we can be more specific.
We are also not recommending prophylaxis at this point in time since we
don't have an etiologic agent, and our treatment recommendations are
nonspecific, basically, utilizing the kinds of empiric treatment that
would be appropriate for any patient with an unexplained pneumonia,
including anti-microbials or anti-virals depending on the clinical
judgment of the treating physician and the isolation and supportive care
that I've already mentioned.
We're also preparing a health alert for passengers returning from areas
where SARS has been diagnosed. The health alert basically advises
travelers that if they become ill with fever within seven days following
their return from the affected area, they should consult their
physician. And, likewise, we're advising physicians where to get
information either through our health alerting mechanism, our hotlines,
or our Web sites where we are supporting the clinical community.
There is no WHO recommendation for travel restriction at this point in
time, but we are advising persons planning nonessential or elective
travel to affected areas that they may wish to postpone their trip until
further notice. So we will provide additional information about travel
advisories at www.cdc.gov/travel, and that will be updated periodically
as we go forward.
So I think again this is an ongoing problem. We're at the very early
stages of the investigation. We have received only a few laboratory
samples at CDC, so we're only in the preliminary stages of looking for
common and atypical organisms that could be contributing. And we're
working with laboratories around the world to give the most expeditious
diagnostic opportunities here a chance to solve this problem.
MR. SKINNER: All right, Gwen, I think we're ready for questions, please.
GWEN: Ladies and gentlemen, if you have a question, please press the "1"
on your touch tone phone. You will hear a tone indicating you have been
placed in Q. If you press "1" prior to this announcement, please do so
again at this time. You may remove yourself at any time by pressing the
pound key. If you're using the speaking phones, please pick up the hand
set before pressing the numbers. Once again, if you have a question,
please press the "1" at this time. One moment please for the first question.
We have a question from Marian Falco with CNN. Please go ahead.
QUESTION: Hi, Dr. Gerberding. Do we know what the--hello, can you hear me?
MR. SKINNER: Now we can hear you.
QUESTION: Good, I'm sorry. What about the time difference between
infection and severe illness and in the couple of cases that we know
about? Do you have any indication--I mean how quickly are people getting
very, very sick?
DR. GERBERDING: Again, this is very preliminary, but the investigation
in Hong Kong and Hanoi suggests that the incubation period is somewhere
between two and seven days on average. You know, we're right now
probably identifying the most severely ill patients, and so we want to
be open to modifying that if we have better data in the future.
QUESTION: And just to get this right, you do not know yet if it's
bacterial or viral infection, correct?
DR. GERBERDING: Correct. We do not have information about the etiology
right now.
CALLER: Thank you.
MR. SKINNER: Next question, please.
GWEN: We have a question from the line of Tom Watkins, CNN. Please go ahead.
QUESTION: Do you know what conference the man in New York was taken off
the plane in Germany was attending, and where he was staying or any of
his contacts?
DR. GERBERDING: That investigation is being coordinated by the New York
City Health Department and New York State Health Department, and so
those details will be forthcoming from them. But I can assure you that
they are aggressively evaluating all potential contacts and exposures.
MR. SKINNER: Next question, please.
GWEN: We have a question from the line of Marilyn Chase, Wall Street
Journal. Please go ahead.
QUESTION: Hi, Dr. Gerberding. Can you tell us the number of confirmed
deaths, and are you ruling out--are you trying to rule out Avian influenza?
DR. GERBERDING: With respect to your first question, we know that this
can be a fatal disease, and we have documentation of specific
individuals that died and with an illness attributable to this. But the
exact number of deaths is not confirmed at this point in time. There are
several, and we are, obviously, putting a high priority on investigating
patients in those areas.
With respect to the Avian flu question, you know that earlier this year
there was documentation of two patients in Hong Kong who had H5N1
influenza, and that was confirmed at CDC in our laboratories as well as
other laboratories globally. However, the test for that virus or for
other influenza viruses so far have not been reported to be positive
from the situation that we are investigating now. So we have no evidence
that this is Avian flu.
MR. SKINNER: Next question, please.
GWEN: We have a question from the line of Rob Stein, Washington Post.
Please go ahead.
QUESTION: Yeah, hi, Dr. Gerberding. I understand that one of the
patients from Canada had just returned from a visit to Atlanta, and I
was wondering what was happening there in response to that.
DR. GERBERDING: You are correct. One of the family members of a patient
in--who traveled to Hong Kong did visit Atlanta and is reported to have
developed respiratory symptoms as they were leaving this country and
returning to Canada. The Georgia State Health Department is
investigating the exposure potential here among contacts and people who
were co-workers of the individual.
In addition, we are working with the airlines to assess the passengers
who may have been on the plane when the individual returned to Canada to
be sure that we're not overlooking an opportunity to test illness or
alert them that they need to seek medical attention should they develop
a fever or other symptoms of illness. So that investigation is being
coordinated by the Georgia State Health Department. We're in touch with
them, and they are very aggressively pursuing all of these lines of
investigation.
MR. SKINNER: Next question, please.
GWEN: We have a question from the line of Elizabeth Cohen, CNN. Please
go ahead.
QUESTION: Thanks for having this press conference. Dr. Gerberding, can
you tell us, is there any reason to think that this is or is not terrorism?
DR. GERBERDING: No, what we know so far about this outbreak is that the
people who appear to be most at risk are either health care workers
taking care of sick people, or family members or household contacts of
those that are affected. That pattern of transmission is what we would
typically expect to see from a contagious respiratory illness or a
flu-like illness. But we have an open mind, and let me emphasize that we
have an open mind and will be keeping an open mind about this as we go
forward. We don't know the cause of this, and until we have laboratory
information to point this in the right direction, we cannot jump to any
conclusions one way or another.
QUESTION: So it sounds like what you're saying is that it's not
necessarily--you don't have any reason to think it's terrorism but you
can't rule out that it's terrorism?
DR. GERBERDING: We're just keeping an open mind.
QUESTION: And also, do we know how contagious? I mean if I was on a
subway car with someone who was ill, could I get it from them, or do you
need to have that close like I'm-taking-care-of-me kind of contact.
DR. GERBERDING: What we know so far from the investigations in progress
are that it's very close personal contact of the type defined by WHO as
having cared for, having lived with, or having had direct contact with
respiratory secretions and body fluids of a person with the diagnosis.
So there is no evidence to suggest that this can be spread through
breath contact or through assemblages of large people; it really seems
to require a fairly direct and sustained contact with a symptomatic
individual.
CALLER: Okay, thank you.
MR. SKINNER: Next question, please.
GWEN: We have a question from the line of Barbara Garcia, ABC News.
Please go ahead.
QUESTION: Hi, Doctor. I have, actually, two questions. How is this
particular strain responding to the antibiotics? And is there an
emergency response plan, domestically?
DR. GERBERDING: What we can say right now about treatment is that there
is no consistent utilization of antibiotics or antiviral therapy in the
areas that have had the most cases, and so we have no real information
to help tell us whether or not anything is having a clinical impact. At
best we could just provide anecdotal suggestions and no data or advice.
So as I said before, our recommendation right now is that patients
presenting with severe pneumonia be treated empirically with the same
anti-microbial regimens that we would normally use when we have an
undiagnosed patient with pneumonia. And we would put a great deal of
emphasis on supportive care and isolation precautions to prevent spread
in those environments.
In terms of the domestic situation, as I said, we're taking steps today
to be on the alert throughout the public health and the medical
community for suspicious cases among people who have traveled through
these areas or who have had direct contact with known cases. And we are
also preparing very specific guidance for clinicians and have assembled
our experts here at CDC with Dr. Hughes and the National Center for
Infectious Disease to bring together the individuals with clinical
perspective as well as epidemiologic perspective to constantly review
and update the guidance that we can issue.
So interim guidance today, ongoing advice and information as we know more.
MR. SKINNER: Next question, please.
GWEN: We have a question from Markie Becker, New York Daily News. Please
go ahead.
QUESTION: Hi. Thanks, Doctor. I have a question about the doctor who was
in New York. Can you tell us exactly when he was in New York and when,
exactly, he was taken off the plane? And also, if other--if anyone else
is showing symptoms at this point?
DR. GERBERDING: Let me just emphasize again that we have no cases under
evaluation or suspicion in the United States at this point in time. That
individual is being evaluated by the New York Health Department, and
they really are the best resource for providing that level of detail.
QUESTION: Okay. Can you tell us anything about the U.S. businessman in
Hong Kong who started presenting with symptoms?
DR. GERBERDING: Very difficult for me to distinguish one patient from
another at this point in time because we have more than 150 patients
under evaluation, so I can't answer that question off the top of my head.
MR. SKINNER: Next question, please.
GWEN: We have a question from the line of Mary Ann Young, AP Washington.
Please go ahead.
QUESTION: I'm on a broadcast line, so first I have to make sure you can
hear me.
MR. SKINNER: Yes, we can hear you just fine.
QUESTION: My question is--it's not a question, Dr. Gerberding. If you
could please, restate those symptoms converting the Celsius degrees of
fever into Fahrenheit.
DR. GERBERDING: The WHO case definition includes a temperature greater
than 38, which is a temperature above 101 degrees (Editor's Note: The
exact conversion from 38 degrees Celsius is 100.4 Fahrenheit), and
cough, shortness of breath, and trouble breathing, and either close
contact with someone who's been diagnosed with this illness or recent
travel to the areas in Asia that are reporting cases.
MR. SKINNER: Okay, does that answer your question?
QUESTION: Yeah, that's great. I needed the correct conversion.
MR. SKINNER: Next question, please, Gwen.
GWEN: We have a question from the line of Martin Ensurink (ph), Signs
Magazine. Please go ahead.
QUESTION: Hi, and thank you. Dr. Gerberding, do you know how many agents
have been definitively ruled out as the culprit in these outbreaks?
DR. GERBERDING: As I said, the laboratory assessment is ongoing, and we
are having an open mind. We have not completely excluded any pathogen at
this point in time. It would be too premature to draw any conclusions
until we have the kinds of specimens and blood, respiratory secretions,
and autopsy samples that we need to really be conclusive.
QUESTION: Does CDC have any of those specimens yet?
DR. GERBERDING: We have a few specimens, and we're in the process of
evaluating them as quickly as we can. But, as you may know, for some
tests--for example, virus cultures that take several days for the
definitive information to become available--and we're working with WHO
to get more specimens. And also the WHO collaborating labs around the
world as well as the Canadian laboratories are in the process of
evaluating samples. We have confidence that these laboratories can do
very sophisticated testing, so, hopefully, information will be coming
forth in the next few days.
MR. SKINNER: Next question, please.
GWEN: We have a question from the line of John Verelli (ph), WCBS.
Please go ahead.
QUESTION: Actually, my question was on the specifics of the New York
case, and I've gotten my answer, basically. I need to call the health
department, so thank you anyway.
MR. SKINNER: Okay, thank you. Next question, please.
GWEN: We have a question from the line of Tom Watkins, CNN. Please go ahead.
QUESTION: Can you describe the course of the illness? What are the
symptoms that start out, and do people get better or have they all just
remained sick? And do you know how many of those 150 odd cases are on
respirators?
DR. GERBERDING: We're in the process of looking into the entire clinical
spectrum with the CDC scientists who are on the ground in the various
affected areas. Some people have recovered from this illness. In
addition, some people have had a very rapidly deteriorating course, and
others appear to gradually get ill and then stay more or less in a
steady state for a period of time. So what we can say right now is it
appears to be variable, and we'll be able to say more in terms of
numerators and denominators when we have more thorough clinical assessment.
QUESTION: And did the cases in China, did that initial outbreak in,
what, February, or in China, has that ended?
DR. GERBERDING: We have very little information about the details of
what occurred in the mainland China outbreak during the winter months.
And as per the Chinese government, we understand that that outbreak is over.
MR. SKINNER: Next question, please.
GWEN: We have a question from the line of Verena Dodnick, Associated
Press, New York. Please go ahead.
QUESTION: Hello, Doctor, and whoever's there. I'm just--I was going to
ask about the New York case, and where is this man now and what were the
dates of his stay in New York, do you know?
DR. GERBERDING: I'm not going to be able to provide you with the
specifics of his travel schedule, but I can tell you that as of this
morning he was in Frankfort where WHO has boarded the airplane that he
was traveling on and is in the process of interviewing him and other
passengers. I believe he's in medical care at this point in time.
QUESTION: Can you tell us what airline he was using?
DR. GERBERDING: No.
MR. SKINNER: Next question, please.
GWEN: We have a question from the line of Mariam Falco, CNN. Please go
ahead.
QUESTION: Thanks for the opportunity for a follow-up. Dr. Gerberding,
Secretary Thompson mentioned that he had been in consultation with some
folks 10 days ago and had a meeting as recently as Thursday. What has
happened in the past three days that made you have this press conference
now and maybe not on Thursday? Has something significantly transpired in
those past three days?
DR. GERBERDING: Yeah, the main urgency for getting information out today
is that the cases are now being reported from a growing number of
countries in Asia, and the case count is going up quite rapidly. But in
addition, we have concerns about movement out of Asia into North America
as we learned about the family in Canada and the travelers to the U.S.
It was important for us to put the domestic public health system and
clinical system on high alert to watch for cases and take necessary steps.
In addition, the travel alert that WHO has issued, has an impact on
domestic travelers, and people will be having questions, so we felt it
was very important to get this information out so that they would be
able to look at these international events in context and not be alarmed
about an exposure risk if they don't fall into the categories where
we're concerned about potential spread.
CALLER: Thank you.
MR. SKINNER: Gwen, I think we have time for one more question, please.
GWEN: We do have a question from the line of Carol Kingstahl (ph), CNN.
Please go ahead.
QUESTION: Thank you, Dr. Gerberding. I actually have two questions. One,
you have mentioned that you're investigating people who have come
through Georgia and through New York. Are there other states where you
have things under investigation? Also, I wish you could speak for a
moment about our global society and how disease travels, it seems like
much more quickly now, and who you feel like you're addressing it now
versus how you would have addressed it, previously?
DR. GERBERDING: The investigations of the patients in Georgia and New
York are the only two cases that we are investigating in the United
States at this point in time. So as of this moment those are the only
two situations that we are aware of. We will not be surprised if
additional situations evolve, and that's part of the reason for putting
our system on alert.
With respect to the global village, I actually am sitting here with Dr.
Jim Hughes, who really is the person is the nation's leader of our
global response to emerging infectious diseases, and I'll just ask him
to answer the last question.
DR. HUGHES: Well, that's an excellent question. This is a very good
example of the sort of global threat that infectious diseases can pose.
And you can see just in the information here as it's developing, you see
the rapidity with which patients can move from one geographic area to
another. So this is a wonderful illustration of the importance of
rebuilding the global disease surveillance and response capacity.
MR. SKINNER: Gwen, I think Dr. Gerberding has something to say in
closing, and then we'll end the call. Dr. Gerberding?
DR. GERBERDING: Yes, thank you. I again just appreciate your doing this
on a Saturday afternoon. I think we would all like to be someplace else
today, but I want to make sure I emphasize one point, and that is that
we have not identified any cases in the United States at this point in
time, but we're thoroughly investigating, and we will be taking
aggressive steps to reach those who have traveled to the affected areas.
And if anybody who's traveled to parts of Asia implicated in this
syndrome has a symptom of fever with respiratory illness, it's very
important that they contact their medical care provider.
MR. SKINNER: Okay. Gwen, this concludes our call. Thank you very much.
For more information, visit the SARS web site.
https://www.cdc.gov/ncidod/sars/
CDC Telebriefing Transcript
CDC's Response to Atypical Pneumonia in
Southeast Asia and Canada
March 15, 2003
MR. SKINNER: Thank you, Gwen, and thank you all for joining us. We're
going to get right to it, and with us on the call is the Secretary of
the Department of Health and Human Services, Mr. Tommy Thompson, who's
going to deliver some brief remarks, and then he has to run. We'll then
turn the call over to Dr. Julie Gerberding, and then we'll take your Q's
and A's.
So Secretary Thompson, please go, please.
SECRETARY THOMPSON: Thank you very much Tom, and Gwen, and Julie, and
Jerry. Thank you very much for allowing me to come on this
teleconference. I'm at O'Hare Airfield, and I'm going to be on a plane
in six minutes to go back to Washington, D.C. But I want to thank all of
you today for taking time today to join us for this telebriefing for an
update on the outbreak of what we consider a very severe acute
respiratory syndrome in Asia. We decided to have this telebriefing on
Saturday because this is a situation that we wanted to involve you in
very quickly, and we want you to have the most updated information.
Health officials around the world are taking this situation very
seriously. In fact, I had a teleconference with the World Health
Organization on Thursday at early morning, and I'm going to have another
one either tomorrow afternoon or Monday morning with the people at World
Health Organization. But under the great leadership of Dr. Julie
Gerberding at the CDC. the Department of Health and Human Services is
applying a full court press to learn more about this outbreak and how it
might impact on the United States.
Staff in the HHS Department and CDC Emergency Operations Center are
already working around the clock to assist officials from the World
Health Organization, as I mentioned, as they respond to this outbreak.
We've also contacted the Ministry of Health, my counterpart in China,
and I had a face-to-face meeting with the Deputy Minister of Health
about a week ago, a week to 10 days ago, asking them to make sure that
they would cooperate with us because we have to have their willingness
and their access into China to make sure that we can get to the root
causes of this particular disease.
We are doing everything humanly possible to learn what is causing this
outbreak, how to treat patients and how to prevent the spread to others.
I hope we're able to get to the bottom of this as soon as possible, as I
know all of you are and, certainly, the people and the wonderful efforts
at CDC.
Now, I'd like to turn this to Dr. Gerberding to provide you more
specifics on how the department is going to respond to this outbreak and
be able to give you updated information. Thank you very much, Julie, for
giving me this opportunity to address this group, and I wish you luck,
and I'll be talking to you as soon as I land in Washington, D.C.
ANNOUNCER: Thanks, sir. We really appreciate you joining in. Have a safe
journey home.
MR. SKINNER: Now I'd like to turn it over to Dr. Julie Gerberding,
Director of CDC. The name is spelled G-E-R-B-E-R-D-I-N-G. And she's
going to take just a few moments to talk a little bit about what we are
doing to organize our response to this outbreak.
DR. GERBERDING: Thank you. I wanted to start by explaining why we are
doing this on a Saturday. I'm fully aware this is not the optimal time
to do a media briefing, but as the Secretary said, the situation is
evolving very quickly, and we really do need to get the information out.
And, hopefully, you will appreciate that getting information out any
time is better than no information.
So we're going to tell you what we know today and recognize that this is
ongoing, and we'll be updating you as regularly as we have new
information. You will also be able to find information on the WHO
website, which is their main mechanism for providing international
summaries of these health data. And we will have links and so forth on
our website as we go forward.
The situation today is that WHO has received reports of more than 150
new or suspected cases of a syndrome called Severe Acute Respiratory
Syndrome, which is basically a very severe pneumonia-like illness that
is being reported from a growing list of countries, including China,
Hong Kong, Indonesia, Philippines, Singapore, Thailand and Vietnam. In
addition, the case reports from Canada. No cases have been identified in
the United States, but travelers through the United States who have been
in contact or have traveled to the affected areas are under
investigation to be sure that their time here did not result in exposure
and an opportunity for persons to acquire the illness in this country.
Obviously, this is a very early stage of the investigation, and given
the high prevalence of travel through Southeast Asia, we are alerting
our public health communities and our clinicians to be on the lookout
for cases, and I'll say in a couple of minutes what some of the other
steps that we are taking are at this point in time.
We have activated CDC's Emergency Operation Center to manage this
complex international multijurisdictional outbreak. Our role is to
assist WHO and health officials in the affected countries, in particular
in the area of epidemiologic investigation, laboratory diagnosis, and
assessment of prevention intervention. We have as our current priority
the detection of new cases using WHO case definition which I'll just
briefly review for you.
WHO is defining a case as someone with a fever greater than 38 degrees
Celsius (Editor's Note: 100.4 degrees Fahrenheit), respiratory symptoms
which could be cough, shortness of breath or difficulty breathing, and
either close contact with someone who's already been diagnosed with this
syndrome or recent travel to areas reporting cases of the syndrome.
We recognize, because we do not have an etiologic diagnosis or a
laboratory test for this illness right now, that this is a nonspecific
case definition and may include people who really don't have the
syndrome at all, may have some other more common respiratory illnesses,
but it is a starting point for investigation. And as we either rule in
or rule out cases as we go forward, the number of cases meeting the
syndrome is expected to change.
Our priority also is on communication. And you can expect us to be
providing you with regular updates as we go forward. As I mentioned, the
Web sites will be good resources, but we are also taking a number of
steps to put information out to a variety of collaborating partners.
These steps include sending health alerts to the public health and the
medical community. Later today we will be issuing guidance to clinicians
about the case definition, the isolation recommendation, and what we can
say about treatment and prophylaxis at this point in time.
We assume that this is spread person to person because we're seeing a
large proportion of the cases in Asia among health care workers who were
caring for the ill patients or household contacts of ill patients. We
are recommending precautions to prevent airborne spreads, droplet spread
and direct contact spread until we have further information. And so that
means we're erring on the side of caution until we can be more specific.
We are also not recommending prophylaxis at this point in time since we
don't have an etiologic agent, and our treatment recommendations are
nonspecific, basically, utilizing the kinds of empiric treatment that
would be appropriate for any patient with an unexplained pneumonia,
including anti-microbials or anti-virals depending on the clinical
judgment of the treating physician and the isolation and supportive care
that I've already mentioned.
We're also preparing a health alert for passengers returning from areas
where SARS has been diagnosed. The health alert basically advises
travelers that if they become ill with fever within seven days following
their return from the affected area, they should consult their
physician. And, likewise, we're advising physicians where to get
information either through our health alerting mechanism, our hotlines,
or our Web sites where we are supporting the clinical community.
There is no WHO recommendation for travel restriction at this point in
time, but we are advising persons planning nonessential or elective
travel to affected areas that they may wish to postpone their trip until
further notice. So we will provide additional information about travel
advisories at www.cdc.gov/travel, and that will be updated periodically
as we go forward.
So I think again this is an ongoing problem. We're at the very early
stages of the investigation. We have received only a few laboratory
samples at CDC, so we're only in the preliminary stages of looking for
common and atypical organisms that could be contributing. And we're
working with laboratories around the world to give the most expeditious
diagnostic opportunities here a chance to solve this problem.
MR. SKINNER: All right, Gwen, I think we're ready for questions, please.
GWEN: Ladies and gentlemen, if you have a question, please press the "1"
on your touch tone phone. You will hear a tone indicating you have been
placed in Q. If you press "1" prior to this announcement, please do so
again at this time. You may remove yourself at any time by pressing the
pound key. If you're using the speaking phones, please pick up the hand
set before pressing the numbers. Once again, if you have a question,
please press the "1" at this time. One moment please for the first question.
We have a question from Marian Falco with CNN. Please go ahead.
QUESTION: Hi, Dr. Gerberding. Do we know what the--hello, can you hear me?
MR. SKINNER: Now we can hear you.
QUESTION: Good, I'm sorry. What about the time difference between
infection and severe illness and in the couple of cases that we know
about? Do you have any indication--I mean how quickly are people getting
very, very sick?
DR. GERBERDING: Again, this is very preliminary, but the investigation
in Hong Kong and Hanoi suggests that the incubation period is somewhere
between two and seven days on average. You know, we're right now
probably identifying the most severely ill patients, and so we want to
be open to modifying that if we have better data in the future.
QUESTION: And just to get this right, you do not know yet if it's
bacterial or viral infection, correct?
DR. GERBERDING: Correct. We do not have information about the etiology
right now.
CALLER: Thank you.
MR. SKINNER: Next question, please.
GWEN: We have a question from the line of Tom Watkins, CNN. Please go ahead.
QUESTION: Do you know what conference the man in New York was taken off
the plane in Germany was attending, and where he was staying or any of
his contacts?
DR. GERBERDING: That investigation is being coordinated by the New York
City Health Department and New York State Health Department, and so
those details will be forthcoming from them. But I can assure you that
they are aggressively evaluating all potential contacts and exposures.
MR. SKINNER: Next question, please.
GWEN: We have a question from the line of Marilyn Chase, Wall Street
Journal. Please go ahead.
QUESTION: Hi, Dr. Gerberding. Can you tell us the number of confirmed
deaths, and are you ruling out--are you trying to rule out Avian influenza?
DR. GERBERDING: With respect to your first question, we know that this
can be a fatal disease, and we have documentation of specific
individuals that died and with an illness attributable to this. But the
exact number of deaths is not confirmed at this point in time. There are
several, and we are, obviously, putting a high priority on investigating
patients in those areas.
With respect to the Avian flu question, you know that earlier this year
there was documentation of two patients in Hong Kong who had H5N1
influenza, and that was confirmed at CDC in our laboratories as well as
other laboratories globally. However, the test for that virus or for
other influenza viruses so far have not been reported to be positive
from the situation that we are investigating now. So we have no evidence
that this is Avian flu.
MR. SKINNER: Next question, please.
GWEN: We have a question from the line of Rob Stein, Washington Post.
Please go ahead.
QUESTION: Yeah, hi, Dr. Gerberding. I understand that one of the
patients from Canada had just returned from a visit to Atlanta, and I
was wondering what was happening there in response to that.
DR. GERBERDING: You are correct. One of the family members of a patient
in--who traveled to Hong Kong did visit Atlanta and is reported to have
developed respiratory symptoms as they were leaving this country and
returning to Canada. The Georgia State Health Department is
investigating the exposure potential here among contacts and people who
were co-workers of the individual.
In addition, we are working with the airlines to assess the passengers
who may have been on the plane when the individual returned to Canada to
be sure that we're not overlooking an opportunity to test illness or
alert them that they need to seek medical attention should they develop
a fever or other symptoms of illness. So that investigation is being
coordinated by the Georgia State Health Department. We're in touch with
them, and they are very aggressively pursuing all of these lines of
investigation.
MR. SKINNER: Next question, please.
GWEN: We have a question from the line of Elizabeth Cohen, CNN. Please
go ahead.
QUESTION: Thanks for having this press conference. Dr. Gerberding, can
you tell us, is there any reason to think that this is or is not terrorism?
DR. GERBERDING: No, what we know so far about this outbreak is that the
people who appear to be most at risk are either health care workers
taking care of sick people, or family members or household contacts of
those that are affected. That pattern of transmission is what we would
typically expect to see from a contagious respiratory illness or a
flu-like illness. But we have an open mind, and let me emphasize that we
have an open mind and will be keeping an open mind about this as we go
forward. We don't know the cause of this, and until we have laboratory
information to point this in the right direction, we cannot jump to any
conclusions one way or another.
QUESTION: So it sounds like what you're saying is that it's not
necessarily--you don't have any reason to think it's terrorism but you
can't rule out that it's terrorism?
DR. GERBERDING: We're just keeping an open mind.
QUESTION: And also, do we know how contagious? I mean if I was on a
subway car with someone who was ill, could I get it from them, or do you
need to have that close like I'm-taking-care-of-me kind of contact.
DR. GERBERDING: What we know so far from the investigations in progress
are that it's very close personal contact of the type defined by WHO as
having cared for, having lived with, or having had direct contact with
respiratory secretions and body fluids of a person with the diagnosis.
So there is no evidence to suggest that this can be spread through
breath contact or through assemblages of large people; it really seems
to require a fairly direct and sustained contact with a symptomatic
individual.
CALLER: Okay, thank you.
MR. SKINNER: Next question, please.
GWEN: We have a question from the line of Barbara Garcia, ABC News.
Please go ahead.
QUESTION: Hi, Doctor. I have, actually, two questions. How is this
particular strain responding to the antibiotics? And is there an
emergency response plan, domestically?
DR. GERBERDING: What we can say right now about treatment is that there
is no consistent utilization of antibiotics or antiviral therapy in the
areas that have had the most cases, and so we have no real information
to help tell us whether or not anything is having a clinical impact. At
best we could just provide anecdotal suggestions and no data or advice.
So as I said before, our recommendation right now is that patients
presenting with severe pneumonia be treated empirically with the same
anti-microbial regimens that we would normally use when we have an
undiagnosed patient with pneumonia. And we would put a great deal of
emphasis on supportive care and isolation precautions to prevent spread
in those environments.
In terms of the domestic situation, as I said, we're taking steps today
to be on the alert throughout the public health and the medical
community for suspicious cases among people who have traveled through
these areas or who have had direct contact with known cases. And we are
also preparing very specific guidance for clinicians and have assembled
our experts here at CDC with Dr. Hughes and the National Center for
Infectious Disease to bring together the individuals with clinical
perspective as well as epidemiologic perspective to constantly review
and update the guidance that we can issue.
So interim guidance today, ongoing advice and information as we know more.
MR. SKINNER: Next question, please.
GWEN: We have a question from Markie Becker, New York Daily News. Please
go ahead.
QUESTION: Hi. Thanks, Doctor. I have a question about the doctor who was
in New York. Can you tell us exactly when he was in New York and when,
exactly, he was taken off the plane? And also, if other--if anyone else
is showing symptoms at this point?
DR. GERBERDING: Let me just emphasize again that we have no cases under
evaluation or suspicion in the United States at this point in time. That
individual is being evaluated by the New York Health Department, and
they really are the best resource for providing that level of detail.
QUESTION: Okay. Can you tell us anything about the U.S. businessman in
Hong Kong who started presenting with symptoms?
DR. GERBERDING: Very difficult for me to distinguish one patient from
another at this point in time because we have more than 150 patients
under evaluation, so I can't answer that question off the top of my head.
MR. SKINNER: Next question, please.
GWEN: We have a question from the line of Mary Ann Young, AP Washington.
Please go ahead.
QUESTION: I'm on a broadcast line, so first I have to make sure you can
hear me.
MR. SKINNER: Yes, we can hear you just fine.
QUESTION: My question is--it's not a question, Dr. Gerberding. If you
could please, restate those symptoms converting the Celsius degrees of
fever into Fahrenheit.
DR. GERBERDING: The WHO case definition includes a temperature greater
than 38, which is a temperature above 101 degrees (Editor's Note: The
exact conversion from 38 degrees Celsius is 100.4 Fahrenheit), and
cough, shortness of breath, and trouble breathing, and either close
contact with someone who's been diagnosed with this illness or recent
travel to the areas in Asia that are reporting cases.
MR. SKINNER: Okay, does that answer your question?
QUESTION: Yeah, that's great. I needed the correct conversion.
MR. SKINNER: Next question, please, Gwen.
GWEN: We have a question from the line of Martin Ensurink (ph), Signs
Magazine. Please go ahead.
QUESTION: Hi, and thank you. Dr. Gerberding, do you know how many agents
have been definitively ruled out as the culprit in these outbreaks?
DR. GERBERDING: As I said, the laboratory assessment is ongoing, and we
are having an open mind. We have not completely excluded any pathogen at
this point in time. It would be too premature to draw any conclusions
until we have the kinds of specimens and blood, respiratory secretions,
and autopsy samples that we need to really be conclusive.
QUESTION: Does CDC have any of those specimens yet?
DR. GERBERDING: We have a few specimens, and we're in the process of
evaluating them as quickly as we can. But, as you may know, for some
tests--for example, virus cultures that take several days for the
definitive information to become available--and we're working with WHO
to get more specimens. And also the WHO collaborating labs around the
world as well as the Canadian laboratories are in the process of
evaluating samples. We have confidence that these laboratories can do
very sophisticated testing, so, hopefully, information will be coming
forth in the next few days.
MR. SKINNER: Next question, please.
GWEN: We have a question from the line of John Verelli (ph), WCBS.
Please go ahead.
QUESTION: Actually, my question was on the specifics of the New York
case, and I've gotten my answer, basically. I need to call the health
department, so thank you anyway.
MR. SKINNER: Okay, thank you. Next question, please.
GWEN: We have a question from the line of Tom Watkins, CNN. Please go ahead.
QUESTION: Can you describe the course of the illness? What are the
symptoms that start out, and do people get better or have they all just
remained sick? And do you know how many of those 150 odd cases are on
respirators?
DR. GERBERDING: We're in the process of looking into the entire clinical
spectrum with the CDC scientists who are on the ground in the various
affected areas. Some people have recovered from this illness. In
addition, some people have had a very rapidly deteriorating course, and
others appear to gradually get ill and then stay more or less in a
steady state for a period of time. So what we can say right now is it
appears to be variable, and we'll be able to say more in terms of
numerators and denominators when we have more thorough clinical assessment.
QUESTION: And did the cases in China, did that initial outbreak in,
what, February, or in China, has that ended?
DR. GERBERDING: We have very little information about the details of
what occurred in the mainland China outbreak during the winter months.
And as per the Chinese government, we understand that that outbreak is over.
MR. SKINNER: Next question, please.
GWEN: We have a question from the line of Verena Dodnick, Associated
Press, New York. Please go ahead.
QUESTION: Hello, Doctor, and whoever's there. I'm just--I was going to
ask about the New York case, and where is this man now and what were the
dates of his stay in New York, do you know?
DR. GERBERDING: I'm not going to be able to provide you with the
specifics of his travel schedule, but I can tell you that as of this
morning he was in Frankfort where WHO has boarded the airplane that he
was traveling on and is in the process of interviewing him and other
passengers. I believe he's in medical care at this point in time.
QUESTION: Can you tell us what airline he was using?
DR. GERBERDING: No.
MR. SKINNER: Next question, please.
GWEN: We have a question from the line of Mariam Falco, CNN. Please go
ahead.
QUESTION: Thanks for the opportunity for a follow-up. Dr. Gerberding,
Secretary Thompson mentioned that he had been in consultation with some
folks 10 days ago and had a meeting as recently as Thursday. What has
happened in the past three days that made you have this press conference
now and maybe not on Thursday? Has something significantly transpired in
those past three days?
DR. GERBERDING: Yeah, the main urgency for getting information out today
is that the cases are now being reported from a growing number of
countries in Asia, and the case count is going up quite rapidly. But in
addition, we have concerns about movement out of Asia into North America
as we learned about the family in Canada and the travelers to the U.S.
It was important for us to put the domestic public health system and
clinical system on high alert to watch for cases and take necessary steps.
In addition, the travel alert that WHO has issued, has an impact on
domestic travelers, and people will be having questions, so we felt it
was very important to get this information out so that they would be
able to look at these international events in context and not be alarmed
about an exposure risk if they don't fall into the categories where
we're concerned about potential spread.
CALLER: Thank you.
MR. SKINNER: Gwen, I think we have time for one more question, please.
GWEN: We do have a question from the line of Carol Kingstahl (ph), CNN.
Please go ahead.
QUESTION: Thank you, Dr. Gerberding. I actually have two questions. One,
you have mentioned that you're investigating people who have come
through Georgia and through New York. Are there other states where you
have things under investigation? Also, I wish you could speak for a
moment about our global society and how disease travels, it seems like
much more quickly now, and who you feel like you're addressing it now
versus how you would have addressed it, previously?
DR. GERBERDING: The investigations of the patients in Georgia and New
York are the only two cases that we are investigating in the United
States at this point in time. So as of this moment those are the only
two situations that we are aware of. We will not be surprised if
additional situations evolve, and that's part of the reason for putting
our system on alert.
With respect to the global village, I actually am sitting here with Dr.
Jim Hughes, who really is the person is the nation's leader of our
global response to emerging infectious diseases, and I'll just ask him
to answer the last question.
DR. HUGHES: Well, that's an excellent question. This is a very good
example of the sort of global threat that infectious diseases can pose.
And you can see just in the information here as it's developing, you see
the rapidity with which patients can move from one geographic area to
another. So this is a wonderful illustration of the importance of
rebuilding the global disease surveillance and response capacity.
MR. SKINNER: Gwen, I think Dr. Gerberding has something to say in
closing, and then we'll end the call. Dr. Gerberding?
DR. GERBERDING: Yes, thank you. I again just appreciate your doing this
on a Saturday afternoon. I think we would all like to be someplace else
today, but I want to make sure I emphasize one point, and that is that
we have not identified any cases in the United States at this point in
time, but we're thoroughly investigating, and we will be taking
aggressive steps to reach those who have traveled to the affected areas.
And if anybody who's traveled to parts of Asia implicated in this
syndrome has a symptom of fever with respiratory illness, it's very
important that they contact their medical care provider.
MR. SKINNER: Okay. Gwen, this concludes our call. Thank you very much.
For more information, visit the SARS web site.
https://www.cdc.gov/ncidod/sars/